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Details on Person Cdh1 (del Valle et al. 2013: recombinant CDH1 of unspecified...

Class:IdSummation:9968622
_displayNameCdh1 (del Valle et al. 2013: recombinant CDH1 of unspecified...
_timestamp2025-10-17 16:38:27
created[InstanceEdit:9968621] Orlic-Milacic, Marija, 2025-10-17
literatureReference[LiteratureReference:9958852] Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts
[LiteratureReference:9968611] Extraneous E-Cadherin Engages the Deterministic Process of Somatic Reprogramming through Modulating STAT3 and Erk1/2 Activity
[LiteratureReference:9968616] E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells
textCdh1 (del Valle et al. 2013: recombinant CDH1 of unspecified species origin, likely mouse, ectopically expressed in mouse embryonic stem cells - mESCs; Liu et al. 2021: recombinant Cdh1 of unspecified species origin, likely mouse, ectopically expressed in mouse embryonic fibroblasts - MEFs) and Cdh11 (Adan et al. 2022: mouse fibroblast cell line Balb/c3T3 and endogenous mouse proteins were used) stabilize Il6st (also known as gp130) protein levels likely by preventing internalization and degradation of Il6st (Liu et al. 2021) through interaction of the extracellular domain of Cdh1 with the Il6st receptor complex (del Valle et al. 2013).
(summation)[BlackBoxEvent:9968619] Il6st protein stabilization by Cdh1,Cdh11 [Mus musculus]
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