Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person KDM1A [nucleoplasm]

Class:IdEntityWithAccessionedSequence:996769
_displayNameKDM1A [nucleoplasm]
_timestamp2013-03-11 16:33:44
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:996739] Jupe, S, 2010-11-08
endCoordinate852
modified[InstanceEdit:3214391] Jupe, S, 2013-03-11
[InstanceEdit:3448660] Wu, G, 2013-05-16
nameKDM1A
Lysine-specific histone demethylase 1A
KDM1A_HUMAN
referenceEntity[ReferenceGeneProduct:144053] UniProt:O60341 KDM1A [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1111615] R-HSA-996769.1
startCoordinate1
(activeUnit)[NegativeGeneExpressionRegulation:9815873] Negative gene expression regulation by 'KDM1A:DNTTIP1:CDH1 gene [nucleoplasm]'
[NegativeGeneExpressionRegulation:9931133] Negative gene expression regulation by 'KDM1A:ZNF217:CDH1 gene'
[CatalystActivity:5625851] histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm]
[CatalystActivity:5625869] histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm]
[CatalystActivity:9011939] histone H3K9 demethylase activity of MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm]
(hasComponent)[Complex:4657015] CoREST complex [nucleoplasm] [Homo sapiens]
[Complex:4657016] BHC complex [nucleoplasm] [Homo sapiens]
[Complex:5625850] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] [Homo sapiens]
[Complex:5625863] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] [Homo sapiens]
[Complex:9011901] MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] [Homo sapiens]
[Complex:9815872] KDM1A:DNTTIP1:CDH1 gene [nucleoplasm] [Homo sapiens]
[Complex:9931128] KDM1A:ZNF217:CDH1 gene [nucleoplasm] [Homo sapiens]
(hasMember)[DefinedSet:5423122] KDM1A,KDM1B [nucleoplasm] [Homo sapiens]
[DefinedSet:9024371] KDM1A, KDM1B, KDM3A, KDM4A [nucleoplasm] [Homo sapiens]
(input)[Reaction:5625849] Demethylase KDM1A binds KLK2 and KLK3 promoters [Homo sapiens]
[Reaction:9011984] KDM1A is recruited to MYC and BCL2 genes [Homo sapiens]
[Reaction:9764826] DNTTIP1 recruits KDM1A to CDH1 gene promoter [Homo sapiens]
[Reaction:9768067] ZNF217 binds CDH1 gene promoter [Homo sapiens]
(output)[Reaction:5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters [Homo sapiens]
[Reaction:9011985] KDM1A demethylates H3 on MYC and BCL genes in response to estrogen [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by KDM1A [nucleoplasm] (996769)
Follow Reactome