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Details on Person GATA3 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:996768
_displayName	GATA3 [nucleoplasm]
_timestamp	2010-12-02 14:51:40
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:996739] Jupe, S, 2010-11-08
endCoordinate	443
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	GATA3 Trans-acting T-cell-specific transcription factor GATA-3 GATA3_HUMAN
referenceEntity	[ReferenceGeneProduct:55338] UniProt:P23771 GATA3 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1108466] R-HSA-996768.1
startCoordinate	1
(activeUnit)	[PositiveGeneExpressionRegulation:9793789] Positive gene expression regulation by 'GATA3:CDH1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9830507] Positive gene expression regulation by 'GATA3:RET gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9976128] Positive gene expression regulation by 'GATA3:CHD4:EP300:p-S243-NFATC2:FOS:JUN:KLF13:MAF:IL4 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9976384] Positive gene expression regulation by 'GATA3:CHD4:EP300:p-S243-NFATC2:IL13 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9976389] Positive gene expression regulation by 'GATA3:IL5 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9976537] Positive gene expression regulation by 'GATA3:CCR8 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9977763] Positive gene expression regulation by 'GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm]'
(hasComponent)	[Complex:8956589] GATA3-TAL1 core complex [nucleoplasm] [Homo sapiens] [Complex:9009057] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] [Homo sapiens] [Complex:9018480] TFF3 gene:FOXA1:GATA3 [nucleoplasm] [Homo sapiens] [Complex:9018491] FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] [Homo sapiens] [Complex:9023820] TFF1 gene:FOXA1:GATA3 [nucleoplasm] [Homo sapiens] [Complex:9038159] ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm] [Homo sapiens] [Complex:9793788] GATA3:CDH1 gene [nucleoplasm] [Homo sapiens] [Complex:9830437] GATA3:RET gene [nucleoplasm] [Homo sapiens] [Complex:9830465] GATA3:PAX2:LHX1 gene [nucleoplasm] [Homo sapiens] [Complex:9976142] GATA3:CHD4:EP300:p-S243-NFATC2:FOS:JUN:KLF13:MAF:IL4 gene [nucleoplasm] [Homo sapiens] List all 15 refering instances
(hasMember)	[DefinedSet:996770] GATA proteins [nucleoplasm] [Homo sapiens] [DefinedSet:6783189] GATA3,IL33 [nucleoplasm] [Homo sapiens] [DefinedSet:6786274] STAT6 upregulated proteins [cytosol] [Homo sapiens] [DefinedSet:8956530] GATA1,GATA2,GATA3 [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9009065] FOXA1 and GATA3 bind to CCND1 promoter [Homo sapiens] [Reaction:9018494] FOXA1 and GATA3 bind TFF genes [Homo sapiens] [BlackBoxEvent:9038163] ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators [Homo sapiens] [Reaction:9768180] GATA3 binds CDH1 gene promoter [Homo sapiens] [Reaction:9830418] GATA3 binds the LHX1 gene [Homo sapiens] [Reaction:9830423] GATA3 binds the RET gene [Homo sapiens] [Reaction:9976129] GATA3, CHD4, EP300, NFATC2 (NFAT1), FOS:JUN (AP-1), KLF13, and MAF bind the IL4 gene [Homo sapiens] [Reaction:9976381] GATA3, CHD4, EP300, and NFATC2 bind the IL13 gene [Homo sapiens] [Reaction:9976390] GATA3 binds the IL5 gene [Homo sapiens] [Reaction:9976406] GATA3, CHD4, and the NuRD complex bind the TBX21 (T-BET) gene [Homo sapiens] List all 12 refering instances
(marker)	[MarkerReference:9926181] GATA3 [nucleoplasm] Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cells
(output)	[BlackBoxEvent:6793975] Expression of GATA3 [Homo sapiens] [BlackBoxEvent:9830371] Expression of GATA3 in the nephric duct [Homo sapiens] [BlackBoxEvent:9976143] STAT6, NFATC2 (NFAT1), and NICD1,2 positively regulate expression of GATA3 [Homo sapiens]
(proteinMarker)	[Cell:9925883] embryonic non-neural surface ectoderm cell [Homo sapiens]
(regulator)	[PositiveGeneExpressionRegulation:9830508] Positive gene expression regulation by 'GATA3 [nucleoplasm]'
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No pathways have been reviewed or authored by GATA3 [nucleoplasm] (996768)