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Details on Person Iodothyronine deiodinase 2 (DIO2) dimer deiodinates the proh...
| Class:Id | Summation:9965637 |
|---|---|
| _displayName | Iodothyronine deiodinase 2 (DIO2) dimer deiodinates the proh... |
| _timestamp | 2025-09-06 08:29:36 |
| created | [InstanceEdit:9965636] Stephan, Ralf, 2025-09-04 |
| modified | [InstanceEdit:9965652] Stephan, Ralf, 2025-09-04 [InstanceEdit:9965855] Stephan, Ralf, 2025-09-06 |
| text | Iodothyronine deiodinase 2 (DIO2) dimer deiodinates the prohormone thyroxine (T4; 3,5,3',5'-tetraiodothyronine) into the biologically active hormone T3 (3,5,3'-triiodothyronine) (Salvatore et al., 1996). It is unclear if glutathione or thioredoxin act as cofactor in vivo. DIO2 is mainly localized in the ER membrane (Baqui et al., 2000; reviewed in Gereben et al., 2008; Sabatino et al., 2021). |
| (summation) | [BlackBoxEvent:9965635] DIO2 dimer deiodinates T4 to T3 [Homo sapiens] |
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No pathways have been reviewed or authored by Iodothyronine deiodinase 2 (DIO2) dimer deiodinates the proh... (9965637)
