Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Class:IdLiteratureReference:9965438
_displayNameAF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis
_timestamp2025-08-29 18:44:56
author[Person:9965429] Park, Jino
[Person:9845994] Schlederer, Michaela
[Person:5672184] Schreiber, Martin
[Person:9965426] Ice, Ryan
[Person:9725266] Merkel, Olaf
[Person:3788036] Bilban, Martin
[Person:9965433] Hofbauer, Sebastian
[Person:4687049] Kim, Soojin
[Person:9965430] Addison, Joseph
[Person:9026136] Zou, Jie
[Person:9965449] Ji, Chunyan
[Person:9965444] Bunting, Silvia T
[Person:9965453] Wang, Zhengqi
[Person:9965451] Shoham, Menachem
[Person:8865479] Huang, Gang
[Person:9965447] Bago-Horvath, Zsuzsanna
[Person:9965428] Gibson, Laura F
[Person:8942431] Rojanasakul, Yon
[Person:9965425] Remick, Scot
[Person:5084095] Ivanov, Alexey
[Person:9965445] Pugacheva, Elena
[Person:8979777] Bunting, Kevin D
[Person:2685320] Moriggl, Richard
[Person:9725276] Kenner, Lukas
[Person:8939550] Tse, William
created[InstanceEdit:9965435] Orlic-Milacic, Marija, 2025-08-29
journalOncotarget
pages20697-710
pubMedIdentifier26079538
titleAF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis
volume6
year2015
(literatureReference)[Reaction:9965427] MLLT11 (AF1Q) forms a complex with TCF7 [Homo sapiens]
[Reaction:9965437] The complex of MLLT11 and TCF7 binds CD44 gene promoter [Homo sapiens]
[BlackBoxEvent:9965483] MLLT11 and TCF7 stimulate CD44 gene expression [Homo sapiens]
[Summation:9965431]

MLLT1 (also known as AF1Q or TCF7C), a small 9 kDa protei...
[Summation:9965470] MLLT11 (AF1Q) enhances the binding affinity of the CTNNB1:TC...
[Summation:9965489]

MLLT11 (AF1Q), which forms a complex with TCF7 and CTNNB1...

[Change default viewing format]
No pathways have been reviewed or authored by AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis (9965438)