Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person IFIT2 binds AU-rich mRNA

Class:IdReaction:9962876
_displayNameIFIT2 binds AU-rich mRNA
_doReleaseTRUE
_timestamp2026-05-28 17:19:21
compartment[Compartment:70101] cytosol
created[InstanceEdit:9962894] Shamovsky, Veronica, 2025-08-11
input[DefinedSet:9962877] AU-rich mRNA regulated by IFIT2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:1015674] IFIT2 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9962861] Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs
[LiteratureReference:9962865] Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms
modified[InstanceEdit:9981401] Shamovsky, Veronica, 2026-02-08
[InstanceEdit:9983638] Shamovsky, Veronica, 2026-02-25
[InstanceEdit:9989199] Shamovsky, Veronica, 2026-05-19
[InstanceEdit:9989501] Shamovsky, Veronica, 2026-05-28
nameIFIT2 binds AU-rich mRNA
output[Complex:9962883] IFIT2:AU-rich mRNA [cytosol] [Homo sapiens]
releaseDate2026-06-17
reviewed[InstanceEdit:9989198] Hyde, Jennifer L, 2026-05-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9962897] R-HSA-9962876.1
summation[Summation:9962874] Interferon-induced protein with tetratricopeptide repeats 2 ...
(hasEvent)[Pathway:9684482] IFIT antiviral response [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by IFIT2 binds AU-rich mRNA (9962876)