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Query author contributions in Reactome

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Details on Person PAX8 binds PAX8 cofactors

Class:IdReaction:9962453
_displayNamePAX8 binds PAX8 cofactors
_doReleaseFALSE
_timestamp2025-09-25 08:29:33
authored[InstanceEdit:9962424] Stephan, Ralf, 2025-08-04
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9962455] Stephan, Ralf, 2025-08-06
input[EntityWithAccessionedSequence:3968418] PAX8 [nucleoplasm] [Homo sapiens]
[CandidateSet:9962296] PAX8 cofactors [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9967044] D'Eustachio, Peter, 2025-09-25
isChimericFALSE
literatureReference[LiteratureReference:9962239] PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis
[LiteratureReference:9962297] SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer
[LiteratureReference:9770740] The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17
[LiteratureReference:9962303] Genome-wide analysis of Pax8 binding provides new insights into thyroid functions
[LiteratureReference:9962402] NF-kappaB p65 subunit mediates lipopolysaccharide-induced Na(+)/I(-) symporter gene expression by involving functional interaction with the paired domain transcription factor Pax8
[LiteratureReference:9965570] Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction
modified[InstanceEdit:9962461] Stephan, Ralf, 2025-08-06
[InstanceEdit:9962477] Stephan, Ralf, 2025-08-07
[InstanceEdit:9963918] Stephan, Ralf, 2025-08-18
[InstanceEdit:9964258] Stephan, Ralf, 2025-08-21
[InstanceEdit:9965572] Stephan, Ralf, 2025-08-31
[InstanceEdit:9965884] Stephan, Ralf, 2025-09-06
[InstanceEdit:9967043] Stephan, Ralf, 2025-09-25
namePAX8 binds PAX8 cofactors
output[Complex:9962267] PAX8:PAX8 cofactors [nucleoplasm] [Homo sapiens]
precedingEvent
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9962456] R-HSA-9962453.1
summation[Summation:9962454] Several co-factors can bind to PAX8. In rat thyroid cells, t...
(hasEvent)[Pathway:9961434] Regulation of iodide transport [Homo sapiens]
(precedingEvent)[Reaction:9962237] PAX8:cofactors binds the SLC5A5 gene [Homo sapiens]
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No pathways have been reviewed or authored by PAX8 binds PAX8 cofactors (9962453)