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Details on Person GMNN binds MCIDAS dimer:E2F4,E2F5:TFDP1

Class:Id	Reaction:9960751
_displayName	GMNN binds MCIDAS dimer:E2F4,E2F5:TFDP1
_doRelease	TRUE
_timestamp	2026-05-08 19:13:12
authored	[InstanceEdit:9962119] Rothfels, Karen, 2025-07-31
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9960753] Rothfels, Karen, 2025-07-16
edited	[InstanceEdit:9962258] Rothfels, Karen, 2025-07-31
input	[EntityWithAccessionedSequence:113554] GMNN [nucleoplasm] [Homo sapiens] [Complex:9960642] MCIDAS dimer:E2F4,E2F5:TFDP1 [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9962310] Orlic-Milacic, Marija, 2025-08-03
isChimeric	FALSE
literatureReference	[LiteratureReference:9960341] Multicilin drives centriole biogenesis via E2f proteins [LiteratureReference:9960729] GemC1 controls multiciliogenesis in the airway epithelium [LiteratureReference:9960693] Transcriptional regulation of multiciliated cell differentiation [LiteratureReference:9960682] Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis [LiteratureReference:9960696] Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression [LiteratureReference:9960673] The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing
modified	[InstanceEdit:9962260] Rothfels, Karen, 2025-08-01 [InstanceEdit:9962312] Rothfels, Karen, 2025-08-03 [InstanceEdit:9988586] Rothfels, Karen, 2026-05-08 [InstanceEdit:9988643] Rothfels, Karen, 2026-05-08
name	GMNN binds MCIDAS dimer:E2F4,E2F5:TFDP1
output	[Complex:9960643] GMNN:MCIDAS dimer:E2F4,E2F5:TFDP1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9960756] MCIDAS dimer binds E2F4, E2F5 and TFDP1 [Homo sapiens] [BlackBoxEvent:9945716] GRHL2-dependent MCIDAS expression [Homo sapiens] [Reaction:9960746] MCIDAS dimerizes [Homo sapiens]
releaseDate	2026-06-17
reviewed	[InstanceEdit:9988641] Dutcher, Susan K, 2026-05-08 [InstanceEdit:9988584] Rayamajhi, Dheeraj, 2026-05-08 [InstanceEdit:9988583] Roy, Sudipto, 2026-05-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9960773] R-HSA-9960751.1
summation	[Summation:9960616] GMNN binds to a complex of MCIDAS, E2F4 or E2F5 and TFDP1 (a...
(hasEvent)	[Pathway:9945556] Transcriptional regulation of multiciliogenesis [Homo sapiens]
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No pathways have been reviewed or authored by GMNN binds MCIDAS dimer:E2F4,E2F5:TFDP1 (9960751)