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Details on Person The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
| Class:Id | LiteratureReference:9958631 |
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| _displayName | The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases |
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| _timestamp | 2025-06-24 06:06:20 |
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| author | [Person:9958614] Exconde, Patrick M
[Person:9958662] Hernandez-Chavez, Claudia
[Person:9958612] Bourne, Christopher M
[Person:9958636] Richards, Rachel M
[Person:9958645] Bray, Mark B
[Person:9958648] Lopez, Jan L
[Person:9958667] Srivastava, Tamanna
[Person:9958655] Egan, Marisa S
[Person:9958637] Zhang, Jenna
[Person:9958622] Yoo, William
[Person:9686120] Shin, Sunny
[Person:9958624] Discher, Bohdana M
[Person:9686113] Taabazuing, Cornelius Y |
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| created | [InstanceEdit:9958641] Shamovsky, Veronica, 2025-06-24 |
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| journal | Cell Rep |
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| pages | 113581 |
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| pubMedIdentifier | 38103201 |
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| title | The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases |
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| volume | 42 |
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| year | 2023 |
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| (literatureReference) | [Pathway:9686114] Non-canonical inflammasome activation [Homo sapiens]
[BlackBoxEvent:9947978] CASP5 cleaves IL18 at D36 [Homo sapiens]
[BlackBoxEvent:9947987] CASP4 cleaves IL18 at D36 [Homo sapiens]
[BlackBoxEvent:9958657] CASP4 cleaves IL1B at D27 [Homo sapiens]
[BlackBoxEvent:9960522] CASP5 cleaves IL1B at D27 [Homo sapiens]
[Summation:9686139] The human genome encodes the inflammatory caspase-1 (CASP1),...
[Summation:9947823] Caspase-4 (CASP4), an inflammatory caspase, is activated whe...
[Summation:9947854] Upon recognition of bacterial lipopolysaccharide (LPS), huma...
[Summation:9947866] Caspase-4 (CASP4) binds intracellular bacterial lipopolysacc...
[Summation:9947867] Once pro-caspase-4 (CASP4) monomers are brought into close p... |
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