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Details on Person C3 binds C3 inhibitors
Class:Id Reaction:9957021
_displayName C3 binds C3 inhibitors
_doRelease TRUE
_timestamp 2025-08-18 14:16:56
authored [InstanceEdit:9853559] Shamovsky, Veronica, 2023-11-17
compartment [Compartment:984] extracellular region
created [InstanceEdit:9957047] Shamovsky, Veronica, 2025-06-17
edited [InstanceEdit:9963520] Shamovsky, Veronica, 2025-08-14
input [Complex:166822] Complement factor 3 [extracellular region] [Homo sapiens] [CandidateSet:9957061] C3 inhibitors [extracellular region]
internalReviewed [InstanceEdit:9960250] D'Eustachio, Peter, 2025-07-08
isChimeric FALSE
literatureReference [LiteratureReference:9957039] Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors [LiteratureReference:9957015] From discovery to approval: A brief history of the compstatin family of complement C3 inhibitors
modified [InstanceEdit:9960362] Shamovsky, Veronica, 2025-07-10 [InstanceEdit:9961908] Shamovsky, Veronica, 2025-07-28 [InstanceEdit:9963970] Shamovsky, Veronica, 2025-08-18
name C3 binds C3 inhibitors
output [Complex:9957071] C3:C3 inhibitors [extracellular region] [Homo sapiens]
previousReviewStatus [ReviewStatus:9821383] three stars
releaseDate 2025-09-18
reviewed [InstanceEdit:9961904] Duan, Huiquan, 2025-07-28
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9957074] R-HSA-9957021.1
summation [Summation:9957044] Uncontrolled activation of the complement system significant...
(hasEvent) [Pathway:174577] Activation of C3 and C5 [Homo sapiens]
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No pathways have been reviewed or authored by C3 binds C3 inhibitors (9957021)