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Details on Person RV-A TLP transitions from non-coated endocytic vesicle to early endosome

Class:IdBlackBoxEvent:9955262
_displayNameRV-A TLP transitions from non-coated endocytic vesicle to early endosome
_doReleaseFALSE
_timestamp2026-01-21 15:44:08
authored[InstanceEdit:9979788] Orlic-Milacic, Marija, 2026-01-21
created[InstanceEdit:9955263] Orlic-Milacic, Marija, 2025-06-10
disease[Disease:3134794] viral infectious disease
input[Complex:9955134] RV-A TLP VP5*:VP8* [endocytic vesicle lumen] [Rotavirus A]
isChimericFALSE
modified[InstanceEdit:9956565] Orlic-Milacic, Marija, 2025-06-13
[InstanceEdit:9956575] Orlic-Milacic, Marija, 2025-06-13
[InstanceEdit:9956590] Orlic-Milacic, Marija, 2025-06-13
[InstanceEdit:9956883] Orlic-Milacic, Marija, 2025-06-16
[InstanceEdit:9957236] Orlic-Milacic, Marija, 2025-06-17
[InstanceEdit:9958090] Orlic-Milacic, Marija, 2025-06-19
[InstanceEdit:9962474] Orlic-Milacic, Marija, 2025-08-06
[InstanceEdit:9962931] Orlic-Milacic, Marija, 2025-08-12
[InstanceEdit:9979789] Orlic-Milacic, Marija, 2026-01-21
nameRV-A TLP transitions from non-coated endocytic vesicle to early endosome
output[Complex:9955265] RV-A TLP VP5*:VP8* [early endosome lumen] [Rotavirus A]
precedingEvent
regulatedBy[PositiveRegulation:9956564] Positive regulation by 'GGC-RAB5:GTP [early endosome membrane]'
[PositiveRegulation:9956582] Positive regulation by 'EEA1 [early endosome membrane]'
[PositiveRegulation:9956881] Positive regulation by 'ESCRT-0 [cytosol]'
[PositiveRegulation:9957218] Positive regulation by 'ESCRT-I [early endosome membrane]'
[PositiveRegulation:9958087] Positive regulation by 'PARD6B:PRKCI [cytosol]'
relatedSpecies[Species:9615053] Rotavirus A
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9955267] R-HSA-9955262.1
structureModified[InstanceEdit:9956565] Orlic-Milacic, Marija, 2025-06-13
[InstanceEdit:9956590] Orlic-Milacic, Marija, 2025-06-13
[InstanceEdit:9956883] Orlic-Milacic, Marija, 2025-06-16
[InstanceEdit:9957236] Orlic-Milacic, Marija, 2025-06-17
[InstanceEdit:9958090] Orlic-Milacic, Marija, 2025-06-19
summation[Summation:9956573]

After internalization, the RV-A TLP of the simian RRV str...

(hasEvent)[Pathway:9819336] Rotavirus A (RV-A) entry via receptor-mediated endocytosis [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9954890] RV-A TLP transitions to mature endosome [Homo sapiens]
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No pathways have been reviewed or authored by RV-A TLP transitions from non-coated endocytic vesicle to early endosome (9955262)