Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide

Class:IdReaction:9954730
_displayNamePELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide
_doReleaseTRUE
_timestamp2025-11-07 01:23:23
authored[InstanceEdit:9954726] May, Bruce, 2025-06-06
compartment[Compartment:70101] cytosol
created[InstanceEdit:9954738] May, Bruce, 2025-06-08
edited[InstanceEdit:9954726] May, Bruce, 2025-06-06
input[Complex:9954699] 80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] [Homo sapiens]
[Complex:9954715] PELO:HBS1L-1:GTP [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9960460] Matthews, Lisa, 2025-07-13
isChimericFALSE
literatureReference[LiteratureReference:9955732] Structural basis of highly conserved ribosome recycling in eukaryotes and archaea
modified[InstanceEdit:9954923] May, Bruce, 2025-06-09
[InstanceEdit:9955739] May, Bruce, 2025-06-11
[InstanceEdit:9955751] May, Bruce, 2025-06-11
[InstanceEdit:9955884] May, Bruce, 2025-06-12
[InstanceEdit:9960462] May, Bruce, 2025-07-13
[InstanceEdit:9962797] May, Bruce, 2025-08-09
[InstanceEdit:9971549] May, Bruce, 2025-11-07
namePELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide
output[Complex:9954724] PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2025-09-18
reviewed[InstanceEdit:9962796] Bennett, Eric J, 2025-08-09
[InstanceEdit:9962794] Ford, Pierce W, 2025-08-09
[InstanceEdit:9971505] Jafarnejad, Seyed Mehdi, 2025-11-07
[InstanceEdit:9971510] McGirr, Tom, 2025-11-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9954747] R-HSA-9954730.2
summation[Summation:9954918] The PELO:HBS1L:GTP (Pelota:HBS1:GTP) complex binds a ribosom...
(hasEvent)[Pathway:9954714] PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA [Homo sapiens]
(precedingEvent)[Reaction:9954919] ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide (9954730)