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Details on Person GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1

Class:IdLiteratureReference:9954254
_displayNameGTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1
_timestamp2025-06-06 22:19:01
author[Person:9954199] Persico, Marco
[Person:9954198] Petrella, Lella
[Person:9954203] Orteca, Nausicaa
[Person:9954236] Di Dato, Antonio
[Person:9954201] Mariani, Marisa
[Person:9954280] Andreoli, Mirko
[Person:9954206] De Donato, Marta
[Person:9704968] Scambia, Giovanni
[Person:8878836] Novellino, Ettore
[Person:9954226] Ferlini, Cristiano
[Person:9954257] Fattorusso, Caterina
created[InstanceEdit:9954263] Shamovsky, Veronica, 2025-06-06
journalEur J Med Chem
pages132-44
pubMedIdentifier25081641
titleGTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1
volume91
year2015
(literatureReference)[RegulationReference:9968563] Negative regulation by 'S-farn-GBP1:GTP [cytosol]' GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1
[Summation:9954258] Proto-oncogene serine/threonine kinase 1 (PIM1) phosphorylat...
[Summation:9962134] The human Guanylate Binding Proteins (GBPs) constitute a fam...
[Summation:9968555] Guanylate-binding protein 1 (GBP1) activity is tightly regul...
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