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| Class:Id | ReferenceGeneProduct:99526 |
|---|---|
| _chainChangeLog | chain:1-374 added on Fri February 6 2015 |
| _displayName | UniProt:Q8TDU9 RXFP4 |
| _timestamp | 2026-02-20 22:37:35 |
| chain | chain:1-374 |
| checksum | 1929EA812C0804DA |
| comment | FUNCTION High affinity receptor for INSL5. Also acts as a receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.INTERACTION Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: Relaxin-3 receptor 2 shortName: RLN3 receptor 2 alternativeName: G-protein coupled receptor 100 alternativeName: G-protein coupled receptor GPCR142 alternativeName: Insulin-like peptide INSL5 receptor alternativeName: Relaxin family peptide receptor 4 |
| geneName | RXFP4 GPCR142 GPR100 RLN3R2 |
| identifier | Q8TDU9 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | RXFP4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8988626] ENSEMBL:ENSG00000173080 RXFP4 [Homo sapiens] |
| secondaryIdentifier | RL3R2_HUMAN B0M0L4 Q3MJB1 Q8NGZ8 |
| sequenceLength | 374 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:444826] RXFP4 [plasma membrane] [Homo sapiens] |
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