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Details on Person Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1

Class:Id	LiteratureReference:9949698
_displayName	Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1
_timestamp	2025-05-26 01:50:39
author	[Person:9948287] Kuroha, Kazushige [Person:9948314] Zinoviev, Alexandra [Person:9948309] Hellen, Christopher U T [Person:9684522] Pestova, Tatyana V
created	[InstanceEdit:9949739] May, Bruce, 2025-05-26
journal	Mol Cell
pages	286-302.e8
pubMedIdentifier	30244831
title	Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1
volume	72
year	2018
(literatureReference)	[Pathway:9948299] Ribosome-associated quality control [Homo sapiens] [Reaction:9948362] LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide [Homo sapiens] [Reaction:9948427] ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide [Homo sapiens] [Pathway:9954709] Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide [Homo sapiens]
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