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Details on Person ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation

Class:IdLiteratureReference:9948288
_displayNameZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
_timestamp2025-05-19 22:26:09
author[Person:9763171] Sundaramoorthy, Elayanambi
[Person:8867998] Leonard, Marilyn
[Person:9948293] Mak, Raymond
[Person:9948310] Liao, Jeffrey
[Person:9948306] Fulzele, Amitkumar
[Person:5336463] Bennett, Eric J
created[InstanceEdit:9948292] May, Bruce, 2025-05-19
journalMol Cell
pages751-760.e4
pubMedIdentifier28132843
titleZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
volume65
year2017
(literatureReference)[Pathway:9948299] Ribosome-associated quality control [Homo sapiens]
[Reaction:9948301] ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit [Homo sapiens]
[Reaction:9948317] ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome [Homo sapiens]
[Pathway:9954716] ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA [Homo sapiens]
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No pathways have been reviewed or authored by ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation (9948288)