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Details on Person ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
| Class:Id | LiteratureReference:9948288 |
| _displayName | ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation |
| _timestamp | 2025-05-19 22:26:09 |
| author | [Person:9763171] Sundaramoorthy, Elayanambi [Person:8867998] Leonard, Marilyn [Person:9948293] Mak, Raymond [Person:9948310] Liao, Jeffrey [Person:9948306] Fulzele, Amitkumar [Person:5336463] Bennett, Eric J |
| created | [InstanceEdit:9948292] May, Bruce, 2025-05-19 |
| journal | Mol Cell |
| pages | 751-760.e4 |
| pubMedIdentifier | 28132843 |
| title | ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation |
| volume | 65 |
| year | 2017 |
| (literatureReference) | [Pathway:9948299] Ribosome-associated quality control [Homo sapiens] [Reaction:9948301] ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit [Homo sapiens] [Reaction:9948317] ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome [Homo sapiens] [Pathway:9954716] ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA [Homo sapiens] |
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