Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP

Class:IdLiteratureReference:9947931
_displayNameHow guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP
_timestamp2025-05-14 12:50:50
author[Person:9947859] Ghosh, Agnidipta
[Person:5676990] Praefcke, Gerrit J K
[Person:165144] Renault, L
[Person:165143] Wittinghofer, A
[Person:9911679] Herrmann, Christian
created[InstanceEdit:9947847] Shamovsky, Veronica, 2025-05-14
journalNature
pages101-4
pubMedIdentifier16511497
titleHow guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP
volume440
year2006
(literatureReference)[Summation:9947897] Guanylate-binding protein 1 (GBP1) membrane binding, dimer f...
[Summation:9953142] Guanylate-binding protein 1 (GBP1) catalyzes a two-step GTP ...
[Summation:9953166] Guanylate-binding protein 1 (GBP1) mediates a two-step hydro...
[Summation:9962134] The human Guanylate Binding Proteins (GBPs) constitute a fam...
[CatalystActivityReference:9947845] GTPase activity of GBP1:GTP:LPS [cytosol] Mechanism of GTPase-activity-induced self-assembly of human guanylate binding protein 1
[Reaction:9947887] GBP1 hydrolyzes GDP [Homo sapiens]
[Reaction:9953173] GMP dissociates from the GBP1 oligomer [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP (9947931)