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Details on Person LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro

Class:IdLiteratureReference:9947873
_displayNameLPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro
_timestamp2025-05-14 12:50:33
author[Person:9947924] Dickinson, Mary S
[Person:9947921] Kutsch, Miriam
[Person:9947855] Sistemich, Linda
[Person:9947910] Hernandez, Dulcemaria
[Person:9947844] Piro, Anthony S
[Person:9947906] Needham, David
[Person:9947935] Lesser, Cammie F
[Person:9911679] Herrmann, Christian
[Person:9947904] Coers, Jörn
created[InstanceEdit:9947847] Shamovsky, Veronica, 2025-05-14
journalProc Natl Acad Sci U S A
pagese2216028120
pubMedIdentifier37023136
titleLPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro
volume120
year2023
(literatureReference)[Reaction:9947934] CASP4 binds exposed LPS on the bacterial surface [Homo sapiens]
[Summation:9947866] Caspase-4 (CASP4) binds intracellular bacterial lipopolysacc...
[Summation:9947880] Upon infection with Gram-negative bacteria, guanylate-bindin...
[Summation:9947894] Guanylate-binding protein complexes, GBP1:GBP2:GBP3:GBP4, ca...
[Summation:9947897] Guanylate-binding protein 1 (GBP1) membrane binding, dimer f...
[Summation:9947986] Guanylate-binding protein 2 (GBP2) is geranylgeranylated at ...
[Summation:9948004] Guanylate-binding protein 1 (GBP1) is farnesylated at cystei...
[Summation:9962134] The human Guanylate Binding Proteins (GBPs) constitute a fam...
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No pathways have been reviewed or authored by LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro (9947873)