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Details on Person Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1

Class:IdLiteratureReference:9947834
_displayNameNucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1
_timestamp2025-05-14 12:50:22
author[Person:9947852] Shydlovskyi, Sergii
[Person:9947903] Zienert, Anke Y
[Person:9947837] Ince, Semra
[Person:9947928] Dovengerds, Christine
[Person:9947874] Hohendahl, Annika
[Person:9947913] Dargazanli, Julia M
[Person:9947853] Blum, Ailisa
[Person:9947915] Günther, Saskia D
[Person:9839081] Kladt, Nikolay
[Person:9947942] Stürzl, Michael
[Person:9839071] Schauss, Astrid C
[Person:9947921] Kutsch, Miriam
[Person:8867982] Roux, Aurélien
[Person:9947943] Praefcke, Gerrit J K
[Person:9911679] Herrmann, Christian
created[InstanceEdit:9947847] Shamovsky, Veronica, 2025-05-14
journalProc Natl Acad Sci U S A
pagesE5559-E5568
pubMedIdentifier28645896
titleNucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1
volume114
year2017
(literatureReference)[Summation:9947871] Guanylate-binding protein 1 (GBP1) localizes to the lipopoly...
[Summation:9947897] Guanylate-binding protein 1 (GBP1) membrane binding, dimer f...
[Summation:9948004] Guanylate-binding protein 1 (GBP1) is farnesylated at cystei...
[Summation:9962134] The human Guanylate Binding Proteins (GBPs) constitute a fam...
[Summation:9968552] In its inactive nucleotide-free state, guanylate-binding pro...
[Polymerisation:9947842] GBP1 hydrolyzes GTP forming GBP1 oligomers [Homo sapiens]
[Reaction:9947932] GBP1:GTP binds LPS on the bacterial surface [Homo sapiens]
[Reaction:9948016] FNTA:FNTB transfers farnesyl to GBP1 [Homo sapiens]
[Reaction:9968553] GBP1 binds GTP [Homo sapiens]
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