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Details on Person Import of DENV RNA from exosomes

Class:IdBlackBoxEvent:9947465
_displayNameImport of DENV RNA from exosomes
_doReleaseTRUE
_timestamp2025-12-03 15:39:02
authored[InstanceEdit:9947460] Stephan, Ralf, 2025-05-06
compartment[Compartment:70101] cytosol
[Compartment:383505] extracellular exosome
created[InstanceEdit:9947460] Stephan, Ralf, 2025-05-06
disease[Disease:3244610] dengue disease
edited[InstanceEdit:9970206] Stephan, Ralf, 2025-10-29
goBiologicalProcess[GO_BiologicalProcess:2132843] macropinocytosis
input[DefinedSet:9947377] DENV RNA [extracellular exosome] [Dengue virus type 2]
internalReviewed[InstanceEdit:9959999] Matthews, Lisa, 2025-07-04
isChimericFALSE
literatureReference[LiteratureReference:9947348] Dissemination of the Flavivirus Subgenomic Replicon Genome and Viral Proteins by Extracellular Vesicles
[LiteratureReference:9947385] Arthropod EVs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein Tsp29Fb
[LiteratureReference:9947464] Dual Role of Extracellular Vesicles as Orchestrators of Emerging and Reemerging Virus Infections
modified[InstanceEdit:9947487] Stephan, Ralf, 2025-05-06
[InstanceEdit:9960001] Stephan, Ralf, 2025-07-04
[InstanceEdit:9960002] Stephan, Ralf, 2025-07-04
[InstanceEdit:9963605] Stephan, Ralf, 2025-08-15
[InstanceEdit:9964205] Stephan, Ralf, 2025-08-20
[InstanceEdit:9966337] Stephan, Ralf, 2025-09-19
[InstanceEdit:9970205] Stephan, Ralf, 2025-10-29
[InstanceEdit:9970207] Stephan, Ralf, 2025-10-29
[InstanceEdit:9970441] Stephan, Ralf, 2025-10-30
[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
[InstanceEdit:9975896] Stephan, Ralf, 2025-12-03
nameImport of DENV RNA from exosomes
output[DefinedSet:9947376] DENV RNA [cytosol] [Dengue virus type 2]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
regulatedBy[PositiveRegulation:9947457] Positive regulation by 'HAVCR1 [plasma membrane]'
[PositiveRegulation:9947463] Positive regulation by 'CD33 [plasma membrane]'
[PositiveRegulation:9947466] Positive regulation by 'TIMD4 [plasma membrane]'
relatedSpecies[Species:3244621] Dengue virus type 2
releaseDate2025-12-08
reviewed[InstanceEdit:9970204] Mansur, Daniel Santos, 2025-10-29
[InstanceEdit:9970439] Roque Ascenção, Fernando, 2025-10-29
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9947468] R-HSA-9947465.2
summation[Summation:9947459] DENV genomic RNA can be transferred by extracellular vesicle...
(hasEvent)[Pathway:9918485] Dengue Virus Attachment and Entry [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9947230] Cap-dependent translation of DENV genomic RNA [Homo sapiens]
[BlackBoxEvent:9947293] IRES-mediated translation of DENV genomic RNA [Homo sapiens]
[Reaction:9947595] HNRNPC binds DENV mRNA [Homo sapiens]
[Reaction:9947632] ILF2:ILF3 binds DENV mRNA [Homo sapiens]
[Reaction:9947672] YBX1 binds DENV mRNA [Homo sapiens]
[Reaction:9947701] ZFP36L1 binds DENV mRNA [Homo sapiens]
[Reaction:9947718] DDX6 binds DENV mRNA [Homo sapiens]
[Reaction:9948218] HDLBP and RRBP1 bind DENV mRNA [Homo sapiens]
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No pathways have been reviewed or authored by Import of DENV RNA from exosomes (9947465)