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Details on Person D'Eustachio, Peter, 2025-05-01
| Class:Id | InstanceEdit:9947129 |
| _displayName | D'Eustachio, Peter, 2025-05-01 |
| _timestamp | 2025-05-01 19:55:03 |
| author | [Person:140934] D'Eustachio, Peter |
| dateTime | 2025-05-01 19:54:57 |
| (created) | [DatabaseIdentifier:9947123] RHEA:24041 [Person:9947124] Pandey, Amit V [LiteratureReference:9947125] Mechanisms of Cytochrome P450-Catalyzed Oxidations [LiteratureReference:9947126] Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components [SimpleEntity:9947127] ferriheme b(1-) [endoplasmic reticulum membrane] [LiteratureReference:9947128] NADPH P450 oxidoreductase: structure, function, and pathology of diseases [Person:9947130] Lu, A Y [Person:9947131] Junk, K W [CatalystActivityReference:9947132] NADPH-hemoprotein reductase activity of POR [endoplasmic reticulum membrane] NADPH P450 oxidoreductase: structure, function, and pathology of diseases [StableIdentifier:9947133] R-ALL-9947127.1 |
| (modified) | [Reaction:76494] POR reduces CYP450:Fe3+ to CYP450:Fe2+ [Homo sapiens] [PathwayDiagram:500339] Diagram of Phase I - Functionalization of compounds, Defective CYP11A1 causes AICSR, Defective CYP11B1 causes AH4, Defective CYP11B2 causes CMO-1 deficiency, Defective CYP19A1 causes AEXS, Defective CYP1B1 causes Glaucoma, Defective CYP21A2 causes AH3, Defective CYP24A1 causes HCAI, Defective CYP26B1 causes RHFCA, Defective CYP26C1 causes FFDD4, Defective CYP2U1 causes SPG56, Defective CYP4F22 causes ARCI5, Defective CYP7B1 causes SPG5A and CBAS3, Defective FMO3 causes TMAU, Defective MAOA causes BRUNS, and Defective TBXAS1 causes GHDD [Summation:6806918] NADPH-cytochrome P450 reductase (POR) was first identified a... [Complex:8957351] CYP450:Fe3+ [endoplasmic reticulum membrane] [Homo sapiens] [Complex:8957354] CYP450:Fe2+ [endoplasmic reticulum membrane] [Homo sapiens] [SimpleEntity:9842692] ferroheme b(2-) [endoplasmic reticulum membrane] |
| (structureModified) | [Reaction:76494] POR reduces CYP450:Fe3+ to CYP450:Fe2+ [Homo sapiens] |
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No pathways have been reviewed or authored by D'Eustachio, Peter, 2025-05-01 (9947129)