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Details on Person D'Eustachio, Peter, 2025-04-30
| Class:Id | InstanceEdit:9947017 |
| _displayName | D'Eustachio, Peter, 2025-04-30 |
| _timestamp | 2025-04-30 21:58:24 |
| author | [Person:140934] D'Eustachio, Peter |
| dateTime | 2025-04-30 21:58:18 |
| (created) | [CatalystActivity:9947012] ligand-gated calcium channel activity of ITPR tetramers [endoplasmic reticulum membrane] [CatalystActivityReference:9947013] guanyl-nucleotide exchange factor activity of RAPGEF3,4:cAMP [plasma membrane] Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential [DatabaseIdentifier:9947014] RHEA:39283 [CatalystActivityReference:9947015] potassium channel inhibitor activity of PKA catalytic subunit [cytosol] Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism [CatalystActivityReference:9947016] potassium channel inhibitor activity of PKA catalytic subunit [cytosol] Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential [DatabaseIdentifier:9947018] RHEA:33180 [DatabaseIdentifier:9947019] RHEA:15422 [CatalystActivity:9947020] potassium channel inhibitor activity of PKA catalytic subunit [cytosol] [ReferenceMolecule:9947021] long-chain fatty acyl-CoA(4-) [ChEBI:83139] |
| (modified) | [SimpleEntity:164991] LCFA-CoA [cytosol] [SimpleEntity:165009] LCFA-CoA [mitochondrial matrix] [Reaction:169680] IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel [Homo sapiens] [CatalystActivity:169682] ligand-gated calcium channel activity of ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] [CatalystActivity:264517] ATP binding activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] [BlackBoxEvent:265166] Exocytosis of Insulin [Homo sapiens] [Reaction:381607] Activated Adenylyl cyclase synthesizes cyclic AMP [Homo sapiens] [BlackBoxEvent:381644] ER calcium channels open in response to activated PKA [Homo sapiens] [Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [Homo sapiens] [BlackBoxEvent:381713] Potassium voltage-gated channels close in reponse to PKA [Homo sapiens] |
| (structureModified) | [Reaction:169680] IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel [Homo sapiens] [BlackBoxEvent:381644] ER calcium channels open in response to activated PKA [Homo sapiens] [BlackBoxEvent:381713] Potassium voltage-gated channels close in reponse to PKA [Homo sapiens] [Reaction:381727] RAP1A exchanges GDP for GTP [Homo sapiens] [Reaction:399998] Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate [Homo sapiens] [Reaction:434381] CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol [Homo sapiens] [Reaction:434382] ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A [Homo sapiens] |
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No pathways have been reviewed or authored by D'Eustachio, Peter, 2025-04-30 (9947017)