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Details on Person Dengue virion:HAVCR1 induces autophagosome formation

Class:IdBlackBoxEvent:9945936
_displayNameDengue virion:HAVCR1 induces autophagosome formation
_doReleaseTRUE
_timestamp2025-10-30 11:39:45
authored[InstanceEdit:9945844] Stephan, Ralf, 2025-04-19
compartment[Compartment:5683628] autophagosome membrane
[Compartment:74700] endosome membrane
created[InstanceEdit:9945933] Stephan, Ralf, 2025-04-20
disease[Disease:3244610] dengue disease
edited[InstanceEdit:9970206] Stephan, Ralf, 2025-10-29
goBiologicalProcess[GO_BiologicalProcess:9016069] autophagosome-endosome fusion
input[Complex:9922606] DENV-2 virion:HAVCR1 [endosome membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9959999] Matthews, Lisa, 2025-07-04
isChimericFALSE
literatureReference[LiteratureReference:9945914] TIM-1 As a Signal Receptor Triggers Dengue Virus-Induced Autophagy
[LiteratureReference:9945946] Single-virus tracking approach to reveal the interaction of Dengue virus with autophagy during the early stage of infection
[LiteratureReference:9945949] Dengue virus and autophagy
[LiteratureReference:9945986] Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders
[LiteratureReference:9947547] Dengue virus induced autophagy is mediated by HMGB1 and promotes viral propagation
[LiteratureReference:9947583] Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs
[LiteratureReference:9947734] Orthoflavivirus infection and the mTOR signaling pathway
[LiteratureReference:9948284] Role of autophagy during the replication and pathogenesis of common mosquito-borne flavi- and alphaviruses
modified[InstanceEdit:9945948] Stephan, Ralf, 2025-04-20
[InstanceEdit:9945985] Stephan, Ralf, 2025-04-21
[InstanceEdit:9947548] Stephan, Ralf, 2025-05-07
[InstanceEdit:9947588] Stephan, Ralf, 2025-05-08
[InstanceEdit:9947730] Stephan, Ralf, 2025-05-12
[InstanceEdit:9948270] Stephan, Ralf, 2025-05-19
[InstanceEdit:9959650] Stephan, Ralf, 2025-07-01
[InstanceEdit:9960001] Stephan, Ralf, 2025-07-04
[InstanceEdit:9963605] Stephan, Ralf, 2025-08-15
[InstanceEdit:9964026] Stephan, Ralf, 2025-08-19
[InstanceEdit:9964204] Stephan, Ralf, 2025-08-20
[InstanceEdit:9966337] Stephan, Ralf, 2025-09-19
[InstanceEdit:9970205] Stephan, Ralf, 2025-10-29
[InstanceEdit:9970207] Stephan, Ralf, 2025-10-29
[InstanceEdit:9970441] Stephan, Ralf, 2025-10-30
[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
nameDengue virion:HAVCR1 induces autophagosome formation
output[Complex:9945920] DENV-2 virion:HAVCR1 [autophagosome membrane] [Homo sapiens]
precedingEvent
regulatedBy[Requirement:9945932] Requirement by 'PIK3R1 [cytosol]'
relatedSpecies[Species:3244621] Dengue virus type 2
releaseDate2025-12-08
reviewed[InstanceEdit:9970204] Mansur, Daniel Santos, 2025-10-29
[InstanceEdit:9970439] Roque Ascenção, Fernando, 2025-10-29
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9945937] R-HSA-9945936.1
summation[Summation:9945922] DENV-containing endosomes deliver DENV to autophagosomes (Ch...
(hasEvent)[Pathway:9918485] Dengue Virus Attachment and Entry [Homo sapiens]
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