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Details on Person The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

Class:IdLiteratureReference:9945142
_displayNameThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
_timestamp2025-04-11 01:46:07
author[Person:5219041] Jenner, Richard G
[Person:9945138] Townsend, Michael J
[Person:9855834] Jackson, Ian
[Person:5219021] Sun, Kaiming
[Person:9945134] Bouwman, Russell D
[Person:2247945] Young, Richard A
[Person:6784651] Glimcher, Laurie H
[Person:9945133] Lord, Graham M
created[InstanceEdit:9945152] May, Bruce, 2025-04-11
journalProc Natl Acad Sci U S A
pages17876-81
pubMedIdentifier19805038
titleThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
volume106
year2009
(literatureReference)[Summation:9942719] TBX21 and RUNX3 activate transcription of IFNG (inferred fro...
[Pathway:9942503] Differentiation of naive CD4+ T cells to T helper 1 cells (Th1 cells) [Homo sapiens]
[Reaction:9942723] TBX21 and RUNX3 bind the IFNG gene [Homo sapiens]
[Reaction:9942910] TBX21 binds the Tumor necrosis factor (TNF) gene [Homo sapiens]
[BlackBoxEvent:9942917] TBX21 positively regulates expression of C-C motif chemokine 3 (CCL3) [Homo sapiens]
[BlackBoxEvent:9942923] TBX21 positively regulates expression of Tumor necrosis factor (TNF) [Homo sapiens]
[Reaction:9942924] TBX21 binds the C-C motif chemokine 3 (CCL3) gene [Homo sapiens]
[Reaction:9942934] TBX21 binds the C-C chemokine receptor type 5 (CCR5) gene [Homo sapiens]
[BlackBoxEvent:9943630] Tbx21 and Runx3 positively regulate the expression of interferon-gamma (Ifng) [Mus musculus]
[Reaction:9945877] TBX21 and RUNX3 bind the IL4 gene [Homo sapiens]
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