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Details on Person Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]' Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

Class:Id	RegulationReference:9943638
_displayName	Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]' Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
_timestamp	2025-03-30 17:05:21
created	[InstanceEdit:9943634] May, Bruce, 2025-03-30
literatureReference	[LiteratureReference:9942689] Role of T-bet in commitment of TH1 cells before IL-12-dependent selection [LiteratureReference:9942766] A distal conserved sequence element controls Ifng gene expression by T cells and NK cells [LiteratureReference:9942759] A novel transcription factor, T-bet, directs Th1 lineage commitment [LiteratureReference:9942668] Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells [LiteratureReference:9942713] The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses
regulation	[PositiveGeneExpressionRegulation:9943635] Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]'
(regulationReference)	[BlackBoxEvent:9943630] Tbx21 and Runx3 positively regulate the expression of interferon-gamma (Ifng) [Mus musculus]
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No pathways have been reviewed or authored by Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]' Role of T-bet in commitment of TH1 cells before IL-12-dependent selection (9943638)