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Details on Person CHD2:MYOD heterodimer dependent MYOG gene expression

Class:Id	BlackBoxEvent:9943620
_displayName	CHD2:MYOD heterodimer dependent MYOG gene expression
_doRelease	TRUE
_timestamp	2025-11-24 20:34:36
authored	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9943619] Rothfels, Karen, 2025-03-30
edited	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
input	[EntityWithAccessionedSequence:9677208] MYOG gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9945020] Orlic-Milacic, Marija, 2025-04-08
isChimeric	FALSE
literatureReference	[LiteratureReference:9943396] Chd2 interacts with H3.3 to determine myogenic cell fate [LiteratureReference:9677086] Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis [LiteratureReference:9943545] Epigenetic Regulation of Myogenesis: Focus on the Histone Variants
modified	[InstanceEdit:9944902] Rothfels, Karen, 2025-04-07 [InstanceEdit:9945052] Rothfels, Karen, 2025-04-09 [InstanceEdit:9974210] Rothfels, Karen, 2025-11-20 [InstanceEdit:9974736] Rothfels, Karen, 2025-11-24
name	CHD2:MYOD heterodimer dependent MYOG gene expression
output	[EntityWithAccessionedSequence:445160] MYOG [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9943571] CHD2 and MYOD heterodimer bind the MYOG gene [Homo sapiens] [Reaction:9943614] CHD2-dependent H3.3 deposition at MYOG gene [Homo sapiens] [Reaction:9943571] CHD2 and MYOD heterodimer bind the MYOG gene [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9943601] Positive gene expression regulation by 'CHD2:MYOD heterodimer: MYOG gene with H3.3 nucleosome [nucleoplasm]'
regulationReference	[RegulationReference:9943603] Positive gene expression regulation by 'CHD2:MYOD heterodimer: MYOG gene with H3.3 nucleosome [nucleoplasm]' Chd2 interacts with H3.3 to determine myogenic cell fate
releaseDate	2026-03-25
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9943622] R-HSA-9943620.1
summation	[Summation:9943621] MYOG gene expression is dependent on MYOD and CHD2, as well ...
(hasEvent)	[Pathway:9943411] CHD1 and CHD2 subfamily [Homo sapiens]
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No pathways have been reviewed or authored by CHD2:MYOD heterodimer dependent MYOG gene expression (9943620)