Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:AP-dsDNA [nucleoplasm]

Class:IdComplex:9943360
_displayNameAPEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:AP-dsDNA [nucleoplasm]
_timestamp2025-03-27 19:57:19
cellType[CellType:9940599] germinal center B cell
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9943318] May, Bruce, 2025-03-27
hasComponent
isChimericFALSE
nameAPEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:AP-dsDNA
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9943371] R-HSA-9943360.1
(input)[Reaction:9943320] APEX2 endonucleolytically cleaves deoxyribose phosphate residue (dRP, abasic site, apurinic/apyrimidinic site, AP site) [Homo sapiens]
(output)[BlackBoxEvent:9943316] PCNA, APEX2, and error-prone DNA polymerase (POLH, POLI, POLZ, REV1) bind dsDNA with a deoxyribose phosphate residue (abasic site, apurinic/apyrimidinic site, AP site) [Homo sapiens]
(physicalEntity)[CatalystActivity:9943330] DNA endonuclease activity, producing 5'-phosphomonoesters of APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:AP-dsDNA [nucleoplasm]
[Change default viewing format]
No pathways have been reviewed or authored by APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:AP-dsDNA [nucleoplasm] (9943360)