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Details on Person APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:single-strand gap-dsDNA [nucleoplasm]

Class:Id	Complex:9943354
_displayName	APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:single-strand gap-dsDNA [nucleoplasm]
_timestamp	2025-03-27 19:57:18
cellType	[CellType:9940599] germinal center B cell
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9943318] May, Bruce, 2025-03-27
hasComponent	[EntityWithAccessionedSequence:9943358] APEX2 [nucleoplasm] [Homo sapiens] [DefinedSet:9943341] POLH,POLI,POLZ,REV1 [nucleoplasm] [Homo sapiens] [Complex:5651993] MonoUb:K164-PCNA homotrimer [nucleoplasm] [Homo sapiens] [Complex:5651984] MonoUb:K164-PCNA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5651986] MonoUb-K164-PCNA [nucleoplasm] [Homo sapiens] [DefinedSet:68524] Ub [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:68439] PCNA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:68439] PCNA [nucleoplasm] [Homo sapiens] [GenomeEncodedEntity:110336] SSB-gap-dsDNA [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
name	APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:single-strand gap-dsDNA
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9943366] R-HSA-9943354.1
(input)	[BlackBoxEvent:9947306] Error-prone DNA polymerase (REV1, POLH, POLI, POLZ) synthesizes DNA across the short single-stranded lesion [Homo sapiens]
(output)	[Reaction:9943350] APEX2 excises 10-12 nucleotides of single-stranded DNA from nicked double-stranded DNA [Homo sapiens]
(physicalEntity)	[CatalystActivity:9947307] DNA-directed DNA polymerase activity of APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:single-strand gap-dsDNA [nucleoplasm]
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No pathways have been reviewed or authored by APEX2:POLH,I,Z,REV1:MonoUb-K164-PCNA:single-strand gap-dsDNA [nucleoplasm] (9943354)