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Details on Person A novel transcription factor, T-bet, directs Th1 lineage commitment
| Class:Id | LiteratureReference:9942759 |
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| _displayName | A novel transcription factor, T-bet, directs Th1 lineage commitment |
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| _timestamp | 2025-03-19 00:33:34 |
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| author | [Person:6804710] Szabo, S J
[Person:5682161] Kim, S T
[Person:9942732] Costa, G L
[Person:8986062] Zhang, X
[Person:9942695] Fathman, C G
[Person:9942690] Glimcher, L H |
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| created | [InstanceEdit:9942682] May, Bruce, 2025-03-19 |
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| journal | Cell |
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| pages | 655-69 |
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| pubMedIdentifier | 10761931 |
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| title | A novel transcription factor, T-bet, directs Th1 lineage commitment |
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| volume | 100 |
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| year | 2000 |
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| (literatureReference) | [Pathway:9942503] Differentiation of naive CD4+ T cells to T helper 1 cells (Th1 cells) [Homo sapiens]
[BlackBoxEvent:9943630] Tbx21 and Runx3 positively regulate the expression of interferon-gamma (Ifng) [Mus musculus]
[BlackBoxEvent:9943794] Tbx21 positively regulates expression of the C-X-C chemokine type 3 receptor (Cxcr3). [Mus musculus]
[Summation:9942691] TBX21 (Beima et al. 2006, Jenner et al. 2009, Henderson et a...
[Summation:9942719] TBX21 and RUNX3 activate transcription of IFNG (inferred fro...
[Summation:9942933] TBX21 directly upregulates expression of the chemokine recep...
[RegulationReference:9943638] Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]' Role of T-bet in commitment of TH1 cells before IL-12-dependent selection |
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