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Details on Person Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

Class:IdLiteratureReference:9942689
_displayNameRole of T-bet in commitment of TH1 cells before IL-12-dependent selection
_timestamp2025-03-19 00:32:39
author[Person:9942756] Mullen, A C
[Person:9942703] High, F A
[Person:9942666] Hutchins, A S
[Person:9942681] Lee, H W
[Person:9942721] Villarino, A V
[Person:9018027] Livingston, D M
[Person:6804493] Kung, A L
[Person:9942733] Cereb, N
[Person:3697945] Yao, T P
[Person:9942767] Yang, S Y
[Person:9942665] Reiner, S L
created[InstanceEdit:9942682] May, Bruce, 2025-03-19
journalScience
pages1907-10
pubMedIdentifier11397944
titleRole of T-bet in commitment of TH1 cells before IL-12-dependent selection
volume292
year2001
(literatureReference)[RegulationReference:9943430] Positive gene expression regulation by 'Tbx21:Il12rb2 gene [nucleoplasm]' T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells
[RegulationReference:9943638] Positive gene expression regulation by 'Tbx21:Runx3:Ifng gene [nucleoplasm]' Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
[Pathway:9942503] Differentiation of naive CD4+ T cells to T helper 1 cells (Th1 cells) [Homo sapiens]
[BlackBoxEvent:9943450] Tbx21 (T-bet) positively regulates expression of Il12rb2 [Mus musculus]
[BlackBoxEvent:9943630] Tbx21 and Runx3 positively regulate the expression of interferon-gamma (Ifng) [Mus musculus]
[Summation:9942691] TBX21 (Beima et al. 2006, Jenner et al. 2009, Henderson et a...
[Summation:9942719] TBX21 and RUNX3 activate transcription of IFNG (inferred fro...
[Summation:9942739] TBX21 binds the IL12RB2 gene, which encodes a subunit of the...
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No pathways have been reviewed or authored by Role of T-bet in commitment of TH1 cells before IL-12-dependent selection (9942689)