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Details on Person Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint

Class:Id	LiteratureReference:9942592
_displayName	Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint
_timestamp	2025-03-18 00:40:56
author	[Person:9942591] Hassepass, Ingo [Person:75433] Voit, Renate [Person:69596] Hoffmann, Ingrid
created	[InstanceEdit:9942593] Orlic-Milacic, Marija, 2025-03-18
journal	J Biol Chem
pages	29824-9
pubMedIdentifier	12759351
title	Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint
volume	278
year	2003
(literatureReference)	[Reaction:69604] Phosphorylation of CDC25A by CHEK1 [Homo sapiens] [Reaction:69608] Phosphorylation of CDC25A by CHEK2 [Homo sapiens] [BlackBoxEvent:9943678] CHEK1 phosphorylates CHEK2-phosphorylated CDC25A [Homo sapiens] [Summation:69605] DNA damage caused by ultraviolet light (UV), ionizing rad... [Summation:69609] DNA damage caused by ionizing radiation (IR) leads to pho... [Summation:9943672] Although CHEK2 depletion stabilizes CDC25A, additional CHEK1... [Summation:9943720] NEK11, isolated as one of the genes whose knockdown overr...
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