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Details on Person Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint

Class:IdLiteratureReference:9942580
_displayNameRegulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint
_timestamp2025-03-17 21:52:57
author[Person:9942579] Goloudina, Anastasia
[Person:2684971] Yamaguchi, Hiroshi
[Person:9942582] Chervyakova, Daria B
[Person:158949] Appella, E
[Person:9617876] Fornace, Albert J
[Person:9008834] Bulavin, Dmitry V
created[InstanceEdit:9942577] Orlic-Milacic, Marija, 2025-03-17
journalCell Cycle
pages473-8
pubMedIdentifier12963847
titleRegulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint
volume2
year2003
(literatureReference)[Summation:69605]

DNA damage caused by ultraviolet light (UV), ionizing rad...
[Summation:212961]

CDC25A protein, a phosphatase required for progression fr...
[Summation:9942588]

p38 MAPK (MAPK14) phosphorylates full-length CDC25A in vi...
[Summation:9943672] Although CHEK2 depletion stabilizes CDC25A, additional CHEK1...
[Summation:9943720]

NEK11, isolated as one of the genes whose knockdown overr...
[Pathway:69601] Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A [Homo sapiens]
[Reaction:69604] Phosphorylation of CDC25A by CHEK1 [Homo sapiens]
[Reaction:9942578] Phosphorylation of CDC25A by p38 MAPK [Homo sapiens]
[BlackBoxEvent:9943678] CHEK1 phosphorylates CHEK2-phosphorylated CDC25A [Homo sapiens]

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