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Details on Person OLIG2, whose expression is highly tissue-specific, seems to ...
| Class:Id | Summation:9942016 |
| _displayName | OLIG2, whose expression is highly tissue-specific, seems to ... |
| _timestamp | 2026-04-01 04:31:37 |
| created | [InstanceEdit:9942010] Orlic-Milacic, Marija, 2025-03-13 |
| literatureReference | [LiteratureReference:9942012] Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells [LiteratureReference:9973083] Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179 |
| modified | [InstanceEdit:9973098] Orlic-Milacic, Marija, 2025-11-14 [InstanceEdit:9986409] Orlic-Milacic, Marija, 2026-04-01 |
| text | OLIG2, whose expression is highly tissue-specific, seems to favor homodimerization over heterodimerization with class A bHLH transcription factors (Lee et al. 2005). An inhibtor of OLIG2 homodimerization, CT-179, prolongs survival in the Sonic Hedgehog group of medulloblastoma organoid-based models (Li et al. 2025). |
| (summation) | [Reaction:9942014] OLIG2 homodimerizes [Homo sapiens] |
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No pathways have been reviewed or authored by OLIG2, whose expression is highly tissue-specific, seems to ... (9942016)