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Details on Person Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

Class:IdLiteratureReference:9941775
_displayNameDegradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
_timestamp2025-03-10 23:13:31
author[Person:9793138] Busino, Luca
[Person:9941753] Donzelli, Maddalena
[Person:9941774] Chiesa, Massimo
[Person:4640958] Guardavaccaro, Daniele
[Person:9941754] Ganoth, Dvora
[Person:9941777] Dorrello, N Valerio
[Person:9941755] Hershko, Avram
[Person:174134] Pagano, Michele
[Person:9632818] Draetta, Giulio F
created[InstanceEdit:9941778] Orlic-Milacic, Marija, 2025-03-10
journalNature
pages87-91
pubMedIdentifier14603323
titleDegradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
volume426
year2003
(literatureReference)[Summation:69605]

DNA damage caused by ultraviolet light (UV), ionizing rad...
[Summation:179124]

Exposure of various human cell lines to ultraviolet (UV) ...
[Summation:179284]

Exposure of various human cell lines to ultraviolet (UV) ...
[Summation:212961]

CDC25A protein, a phosphatase required for progression fr...
[Summation:9943720]

NEK11, isolated as one of the genes whose knockdown overr...
[Reaction:69598] Ubiquitination of phosphorylated CDC25A [Homo sapiens]
[BlackBoxEvent:69600] Proteolytic degradation of ubiquitinated-Cdc25A [Homo sapiens]
[Pathway:69601] Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A [Homo sapiens]
[Reaction:69604] Phosphorylation of CDC25A by CHEK1 [Homo sapiens]

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