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Query author contributions in Reactome

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Details on Person HDAC1, 2 bind MTA1, 2, 3 and RBBP4,7

Class:IdReaction:9938418
_displayNameHDAC1, 2 bind MTA1, 2, 3 and RBBP4,7
_doReleaseTRUE
_timestamp2025-11-20 21:04:09
authored[InstanceEdit:9938088] Rothfels, Karen, 2025-02-10
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9938419] Rothfels, Karen, 2025-02-14
edited[InstanceEdit:9938088] Rothfels, Karen, 2025-02-10
input[DefinedSet:4657019] MTA1, MTA2, MTA3 [nucleoplasm] [Homo sapiens]
[DefinedSet:4657019] MTA1, MTA2, MTA3 [nucleoplasm] [Homo sapiens]
[DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens]
[DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens]
[DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens]
[DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens]
[DefinedSet:9938420] HDAC1,HDAC2 [nucleoplasm] [Homo sapiens]
[DefinedSet:9938420] HDAC1,HDAC2 [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9945020] Orlic-Milacic, Marija, 2025-04-08
isChimericFALSE
literatureReference[LiteratureReference:9938360] The structure of the core NuRD repression complex provides insights into its interaction with chromatin
[LiteratureReference:9938353] The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture
[LiteratureReference:9938340] The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7
[LiteratureReference:9938323] Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex
[LiteratureReference:9938278] A NuRD for all seasons
[LiteratureReference:9938368] Towards an understanding of the structure and function of MTA1
[LiteratureReference:9938283] Class I HDACs share a common mechanism of regulation by inositol phosphates
[LiteratureReference:9938298] Deciphering the dual roles of PHD finger proteins from oncogenic drivers to tumor suppressors
[LiteratureReference:9749188] The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome
[LiteratureReference:9938305] Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants
[LiteratureReference:9938365] The topology of chromatin-binding domains in the NuRD deacetylase complex
[LiteratureReference:9938333] Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46
[LiteratureReference:9938313] FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1
[LiteratureReference:9938279] A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex
[LiteratureReference:9938325] Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex
[LiteratureReference:9938331] Structural and functional insights into the human Börjeson-Forssman-Lehmann syndrome-associated protein PHF6
[LiteratureReference:9938289] Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex
modified[InstanceEdit:9945052] Rothfels, Karen, 2025-04-09
[InstanceEdit:9974211] Rothfels, Karen, 2025-11-20
nameHDAC1, 2 bind MTA1, 2, 3 and RBBP4,7
output[Complex:9938417] HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] [Homo sapiens]
releaseDate2026-03-25
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9938423] R-HSA-9938418.1
summation[Summation:9938421] The NuRD complex is assembled on the core consisting of the ...
(hasEvent)[Pathway:9937850] NuRD complex assembly [Homo sapiens]
(precedingEvent)[Reaction:9938437] PWWP2A, PWWP2B bind HDAC1,2:MTA1,MTA2,MTA3:RPPB4,RPPB7 [Homo sapiens]
[Reaction:9940462] MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex [Homo sapiens]
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No pathways have been reviewed or authored by HDAC1, 2 bind MTA1, 2, 3 and RBBP4,7 (9938418)
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