Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person DHRSX reduces dolichal to dolichol

Class:Id	Reaction:9937340
_displayName	DHRSX reduces dolichal to dolichol
_doRelease	TRUE
_timestamp	2025-02-26 19:05:09
authored	[InstanceEdit:9937271] D'Eustachio, Peter, 2025-01-29
catalystActivity	[CatalystActivity:9937342] alcohol dehydrogenase (NADP+) activity of DHRSX [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9937341] aldo-keto reductase (NADPH) activity of DHRSX [endoplasmic reticulum membrane] A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis
compartment	[Compartment:5263266] cytoplasmic side of endoplasmic reticulum membrane [Compartment:70101] cytosol [Compartment:171062] early endosome membrane
created	[InstanceEdit:9937336] D'Eustachio, Peter, 2025-01-30
crossReference	[DatabaseIdentifier:9937338] RHEA:80733
edited	[InstanceEdit:9938253] D'Eustachio, Peter, 2025-02-11
input	[SimpleEntity:9937289] DCHAL [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9937278] A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis
modified	[InstanceEdit:9937346] D'Eustachio, Peter, 2025-01-30 [InstanceEdit:9939398] D'Eustachio, Peter, 2025-02-26 [InstanceEdit:9939400] D'Eustachio, Peter, 2025-02-26
name	DHRSX reduces dolichal to dolichol a di-trans,poly-cis-dolichal + NADPH + H(+) => a di-trans,poly-cis-dolichol + NADP(+)
output	[SimpleEntity:449221] DCHOL [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:29366] NADP+ [cytosol]
precedingEvent	[Reaction:9937295] SRD5A3 reduces polyprenal to dolichal [Homo sapiens] [Reaction:9937298] DHRSX oxidizes polyprenol to polyprenal [Homo sapiens]
releaseDate	2025-03-26
reviewed	[InstanceEdit:9939401] Hill, David P, 2025-02-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9937345] R-HSA-9937340.1
summation	[Summation:9937339] DHRSX (Polyprenol dehydrogenase) catalyzes the reduction of ...
(hasEvent)	[Pathway:446199] Synthesis of dolichyl-phosphate [Homo sapiens]
(precedingEvent)	[Reaction:446195] DOLK phosphorylates DCHOL to DOLP [Homo sapiens]
(replacementInstances)	[_Deleted:9937351] Deletion of instance: 4419979
[Change default viewing format]

No pathways have been reviewed or authored by DHRSX reduces dolichal to dolichol (9937340)