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Details on Person D'Eustachio, Peter, 2025-01-30
| Class:Id | InstanceEdit:9937296 |
| _displayName | D'Eustachio, Peter, 2025-01-30 |
| _timestamp | 2025-01-30 13:42:23 |
| author | [Person:140934] D'Eustachio, Peter |
| dateTime | 2025-01-30 13:42:16 |
| (created) | [InstanceEdit:9937271] D'Eustachio, Peter, 2025-01-29 [Person:9937272] Costain, Gregory [Person:9937273] Yoon, Grace [EntityWithAccessionedSequence:9937274] DHRSX [endoplasmic reticulum membrane] [Homo sapiens] [Person:9937275] Schulz, Céline [Person:9937276] Cimbalistiene, Loreta [Person:9937277] Caligiore, Francesco [LiteratureReference:9937278] A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis [LiteratureReference:9937279] The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae [DatabaseIdentifier:9937280] RHEA:80720 |
| (internalReviewed) | [Reaction:140791] activated thrombin (factor IIa) + antithrombin III:heparan sulfate -> thrombin:antithrombin III:heparan sulfate [Homo sapiens] [Pathway:9769726] Defects of Coagulation cascade [Homo sapiens] [Pathway:9769735] Initiation of coagulation cascade [Homo sapiens] [Pathway:9769740] Coagulation pathway [Homo sapiens] [Reaction:9822522] factor VIII -> factor VIIIa + factor VIII B chain+ factor VIII A3 acidic polypeptide +VWF multimer (TF:FVIIa:FXa catalyst) [Homo sapiens] [Pathway:9853846] Defective ANO6 does not expose PS, PE on the platelet membrane [Homo sapiens] [FailedReaction:9853849] Defective ANO6 does not expose PS, PE on the platelet membrane [Homo sapiens] [Reaction:9929054] TF:FVIIa:FIXa ->TF:FVIIa + FIXa [Homo sapiens] [FailedReaction:9930440] F5 R334T, I387T is not cleaved by activated protein C [Homo sapiens] [Pathway:9930449] Defective cleavage of FV variant at a.a.534 [Homo sapiens] |
| (modified) | [ReferenceMolecule:37843] polyprenyl diphosphate [ChEBI:37531] [SimpleEntity:191403] MVA5PP [cytosol] [Reaction:191414] MVD decarboxylates MVA5PP to IPPP [Homo sapiens] [Pathway:446199] Synthesis of dolichyl-phosphate [Homo sapiens] [PathwayDiagram:548980] Diagram of Asparagine N-linked glycosylation, Defective ALG1 causes CDG-1k, Defective ALG11 causes CDG-1p, Defective ALG2 causes CDG-1i, Defective DPAGT1 causes CDG-1j, CMSTA2, Defective GFPT1 causes CMSTA1, Defective MPI causes MPI-CDG, Defective PMM2 causes PMM2-CDG, Defective ALG12 causes CDG-1g, Defective ALG3 causes CDG-1d, Defective ALG6 causes CDG-1c, Defective ALG8 causes CDG-1h, Defective ALG9 causes CDG-1l, Defective DPM1 causes DPM1-CDG, Defective DPM2 causes DPM2-CDG, Defective DPM3 causes DPM3-CDG, Defective MPDU1 causes CDG-1f, Defective RFT1 causes CDG-1n, Defective DHDDS causes RP59, Defective DOLK causes DOLK-CDG, Defective SRD5A3 causes SRD5A3-CDG, KHRZ, Defective B4GALT1 causes CDG-2d, Defective MAN1B1 causes MRT15, Defective MGAT2 causes CDG-2a, Defective MOGS causes CDG-2b, and Defective ALG14 causes ALG14-CMS [SimpleEntity:1131186] mevalonate-5-PP [cytoplasm] [Reaction:4419978] DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP [Homo sapiens] [SimpleEntity:4419982] pPPP [cytoplasmic side of endoplasmic reticulum membrane] [Reaction:4419986] Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL [Homo sapiens] [Summation:4420025] In mammals, polyprenol pyrophosphate (pPPP) requires dephosp... |
| (reviewed) | [Reaction:158137] factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer [Homo sapiens] |
| (structureModified) | [Pathway:446199] Synthesis of dolichyl-phosphate [Homo sapiens] [Reaction:4419978] DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP [Homo sapiens] |
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No pathways have been reviewed or authored by D'Eustachio, Peter, 2025-01-30 (9937296)