Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person CDK5RAP1 thiomethylates dimethylallyladenosine-37 of mitochondrial tRNA(Ser)(UCN) (MT-TS1)

Class:Id	BlackBoxEvent:9937017
_displayName	CDK5RAP1 thiomethylates dimethylallyladenosine-37 of mitochondrial tRNA(Ser)(UCN) (MT-TS1)
_timestamp	2025-01-28 21:58:09
authored	[InstanceEdit:9936974] May, Bruce, 2025-01-25
catalystActivity	[CatalystActivity:9936947] methylthiotransferase activity of CDK5RAP1:4Fe-4S [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9936995] May, Bruce, 2025-01-28
edited	[InstanceEdit:9936974] May, Bruce, 2025-01-25
inferredFrom	[BlackBoxEvent:9936978] Cdk5rap1 thiomethylates dimethylallyladenosine-37 of mitochondrial TRAN(Ser)(UCN) (MT-TS1) [Mus musculus]
input	[EntityWithAccessionedSequence:9937016] N6-dimethylallylA37-MT-TS1 [mitochondrial matrix] [Homo sapiens] [SimpleEntity:2162265] AdoMet [mitochondrial matrix] [SimpleEntity:2162265] AdoMet [mitochondrial matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:9936989] The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA
name	CDK5RAP1 thiomethylates dimethylallyladenosine-37 of mitochondrial tRNA(Ser)(UCN) (MT-TS1)
output	[EntityWithAccessionedSequence:9937023] 2-methylthio-N6-dimethylallylA37-MT-TS1 [mitochondrial matrix] [Homo sapiens] [SimpleEntity:6793613] 5dAde [mitochondrial matrix] [SimpleEntity:2162252] AdoHcy [mitochondrial matrix] [SimpleEntity:379705] L-Met [mitochondrial matrix]
precedingEvent	[Reaction:6787567] TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) [Homo sapiens] [Reaction:6786881] TRNT1 polymerizes CCA at the 3' end of pre-tRNA [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9937065] R-HSA-9937017.1
summation	[Summation:9936982] CDK5RAP1, a homolog of bacterial miaB, is a SAM radical enzy...
(hasEvent)	[Pathway:6787450] tRNA modification in the mitochondrion [Homo sapiens] [Pathway:9936280] Mitochondrial tRNA modification-additional reactions [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by CDK5RAP1 thiomethylates dimethylallyladenosine-37 of mitochondrial tRNA(Ser)(UCN) (MT-TS1) (9937017)