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Details on Person NEXT homodimer [nucleoplasm]

Class:Id	Complex:9935998
_displayName	NEXT homodimer [nucleoplasm]
_timestamp	2025-01-19 20:23:41
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9935987] May, Bruce, 2025-01-19
hasComponent	[Complex:8985567] RBM7:ZCCHC8:SKIV2L2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8985564] RBM7 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6791189] SKIV2L2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8985573] ZCCHC8 [nucleoplasm] [Homo sapiens] [Complex:8985567] RBM7:ZCCHC8:SKIV2L2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8985564] RBM7 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6791189] SKIV2L2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8985573] ZCCHC8 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9935991] Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
name	NEXT homodimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9936005] R-HSA-9935998.1
(hasComponent)	[Complex:9930060] NEXT:ZC3H4:CBCA:m7GpppN-RNA [nucleoplasm] [Homo sapiens] [Complex:9930062] NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] [Homo sapiens] [Complex:9934534] RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] [Homo sapiens] [Complex:9935306] RNA exosome:NEXT:ZC3H4:CBCA:m7GpppN-RNA [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9930056] The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA [Homo sapiens] [Reaction:9930059] The NEXT complex binds ZC3H4:WDR82:CBCA:m7GpppN-RNA [Homo sapiens]
(output)	[BlackBoxEvent:9934763] The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA [Homo sapiens] [BlackBoxEvent:9935290] The RNA exosome in RNA exosome:NEXT:ZC3H4:WDR82:CBCA:capped RNA hydrolyzes capped RNA [Homo sapiens]
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No pathways have been reviewed or authored by NEXT homodimer [nucleoplasm] (9935998)