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Details on Person Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Class:IdLiteratureReference:9935530
_displayNameBasolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress
_timestamp2025-01-15 18:06:54
author[Person:9935535] Lu, Meng
[Person:9935528] Wu, Jiao
[Person:9935534] Hao, Zhi-Wei
[Person:9935533] Shang, Yu-Kui
[Person:5676137] Xu, Jing
[Person:9935529] Nan, Gang
[Person:5423068] Li, Xia
[Person:9644525] Chen, Zhi-Nan
[Person:9935531] Bian, Huijie
created[InstanceEdit:9935532] Orlic-Milacic, Marija, 2025-01-15
journalHepatology
pages317-332
pubMedIdentifier29356040
titleBasolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress
volume68
year2018
(literatureReference)[Pathway:9766229] Degradation of CDH1 [Homo sapiens]
[Reaction:9934751] CDH1 is phosphorylated on tyrosine residues [Homo sapiens]
[Reaction:9934753] CBLL1 ubiquitinates CDH1 [Homo sapiens]
[Reaction:9934755] CBLL1 binds p-Y-CDH1 [Homo sapiens]
[BlackBoxEvent:9935547] Lysosomal degradation of ubiquitinated CDH1 [Homo sapiens]
[BlackBoxEvent:9935552] Ubiquitinated CDH1 translocates to lysosomes for degradation [Homo sapiens]
[Reaction:9958889] SRC phosphorylates CDH1 [Homo sapiens]
[Summation:9934827]

In the canine MDCK cell line, CDH1 (E-cadherin) and CTNNB...
[Summation:9935076] A recombinant mouse CBLL1 (Hakai), an E3 ubiquitin ligase, w...
[Summation:9935114]

In the canine cell line MDCK, endogenous CBLL1 (Hakai), a...

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