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Details on Person Proteolysis of K48polyUb,p-S-Cry1,2

Class:Id	BlackBoxEvent:9934892
_displayName	Proteolysis of K48polyUb,p-S-Cry1,2
_doRelease	TRUE
_timestamp	2025-02-18 21:09:19
authored	[InstanceEdit:9934882] May, Bruce, 2025-01-11
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9934885] May, Bruce, 2025-01-12
edited	[InstanceEdit:9934882] May, Bruce, 2025-01-11
input	[DefinedSet:517929] K48polyUb,p-S-Cry1,2 [nucleoplasm] [Mus musculus]
internalReviewed	[InstanceEdit:9936833] Matthews, Lisa, 2025-01-27
isChimeric	FALSE
literatureReference	[LiteratureReference:400236] SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins [LiteratureReference:9932516] Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm [LiteratureReference:9932876] FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes [LiteratureReference:879775] AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
modified	[InstanceEdit:9935063] May, Bruce, 2025-01-12 [InstanceEdit:9936865] May, Bruce, 2025-01-27 [InstanceEdit:9938453] May, Bruce, 2025-02-14 [InstanceEdit:9938517] May, Bruce, 2025-02-17 [InstanceEdit:9938697] May, Bruce, 2025-02-18
name	Proteolysis of K48polyUb,p-S-Cry1,2
output	[CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus] [CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus] [CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9934894] R-MMU-9934892.1
summation	[Summation:9934883] The proteasome degrades K48-polyubiquitinylated Cry1 and Cry...
(inferredFrom)	[BlackBoxEvent:9934884] Proteolysis of K48polyUb,p-S-CRY1,2 [Homo sapiens]
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No pathways have been reviewed or authored by Proteolysis of K48polyUb,p-S-Cry1,2 (9934892)