Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person RORA and RORC bind ROR response elements (RREs, ROREs) in th...
| Class:Id | Summation:9934781 |
|---|---|
| _displayName | RORA and RORC bind ROR response elements (RREs, ROREs) in th... |
| _timestamp | 2025-01-10 16:17:44 |
| created | [InstanceEdit:9934776] May, Bruce, 2025-01-10 |
| text | RORA and RORC bind ROR response elements (RREs, ROREs) in the NR1D1 promoter and enhance transcription (inferred from mouse homologs). NR1D1 binds its own promoter and negatively regulates expression (Adelmant et al. 1996). Transcription of the NR1D1 gene occurs on the opposite strand of the ERBA gene (Lazar et al.1990). In the human brain, expression of NR1D1 peaks in the early morning, before the peak of PER1 expression (Li et al. 2013) and earlier than the peak of expression of mouse Nr1d1. |
| (summation) | [BlackBoxEvent:9934780] RORA,C positively regulate expression and NR1D1 negatively regulates expression of NR1D1 (REV-ERBA) [Homo sapiens] |
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No pathways have been reviewed or authored by RORA and RORC bind ROR response elements (RREs, ROREs) in th... (9934781)
