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Details on Person Ubiquitinated CDH1 is endocytosed

Class:IdBlackBoxEvent:9934752
_displayNameUbiquitinated CDH1 is endocytosed
_doReleaseTRUE
_timestamp2025-12-01 19:37:57
authored[InstanceEdit:9934754] Orlic-Milacic, Marija, 2025-01-10
compartment[Compartment:876] plasma membrane
[Compartment:74700] endosome membrane
created[InstanceEdit:9934754] Orlic-Milacic, Marija, 2025-01-10
edited[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17
input[Complex:9935237] CBLL1:PolyUb-p-2Y-CDH1 [plasma membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimericFALSE
literatureReference[LiteratureReference:9935106] Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent
[LiteratureReference:9934839] An acidic extracellular pH disrupts adherens junctions in HepG2 cells by Src kinases-dependent modification of E-cadherin
[LiteratureReference:9935502] Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway
modified[InstanceEdit:9935077] Orlic-Milacic, Marija, 2025-01-13
[InstanceEdit:9935116] Orlic-Milacic, Marija, 2025-01-13
[InstanceEdit:9935139] Orlic-Milacic, Marija, 2025-01-13
[InstanceEdit:9935424] Orlic-Milacic, Marija, 2025-01-14
[InstanceEdit:9935506] Orlic-Milacic, Marija, 2025-01-15
[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17
[InstanceEdit:9935647] Orlic-Milacic, Marija, 2025-01-17
[InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20
[InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
[InstanceEdit:9975426] Orlic-Milacic, Marija, 2025-12-01
nameUbiquitinated CDH1 is endocytosed
output[Complex:9935413] CBLL1:PolyUb-p-2Y-CDH1 [early endosome membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2025-06-18
reviewed[InstanceEdit:9975417] Raptis, Leda, 2025-11-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9934756] R-HSA-9934752.2
structureModified[InstanceEdit:9935424] Orlic-Milacic, Marija, 2025-01-14
summation[Summation:9935073] Ectopic overexpression of a recombinant mouse CBLL1 (Hakai),...
(hasEvent)[Pathway:9766229] Degradation of CDH1 [Homo sapiens]
[Pathway:9958810] SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9935552] Ubiquitinated CDH1 translocates to lysosomes for degradation [Homo sapiens]
(updatedInstance)[_UpdateTracker:9984619] Update Tracker - [BlackBoxEvent:9934752] Ubiquitinated CDH1 is endocytosed - v96:[modifyText]
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No pathways have been reviewed or authored by Ubiquitinated CDH1 is endocytosed (9934752)
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