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Details on Person CDH1-associated CTNNA1 binds F-actin

Class:Id	Reaction:9934486
_displayName	CDH1-associated CTNNA1 binds F-actin
_doRelease	TRUE
_timestamp	2025-12-01 16:54:34
authored	[InstanceEdit:9817331] Orlic-Milacic, Marija, 2022-09-15
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9934483] Orlic-Milacic, Marija, 2025-01-08
edited	[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17
input	[Complex:9934413] Homotypic CDH1 cis-cluster [plasma membrane] [Homo sapiens] [Polymer:9913263] F-actin (all) [cytosol] [Homo sapiens] [Polymer:9913263] F-actin (all) [cytosol] [Homo sapiens] [Polymer:9913263] F-actin (all) [cytosol] [Homo sapiens] [Polymer:9913263] F-actin (all) [cytosol] [Homo sapiens] [Polymer:9913263] F-actin (all) [cytosol] [Homo sapiens]
internalReviewed	[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimeric	FALSE
literatureReference	[LiteratureReference:9934437] Actin-delimited adhesion-independent clustering of E-cadherin forms the nanoscale building blocks of adherens junctions [LiteratureReference:9934488] alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells
modified	[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17 [InstanceEdit:9935647] Orlic-Milacic, Marija, 2025-01-17 [InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20 [InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23 [InstanceEdit:9975419] Orlic-Milacic, Marija, 2025-12-01
name	CDH1-associated CTNNA1 binds F-actin
output	[Complex:9934481] Homotypic CDH1 cis-cluster:F-actin [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9934411] CDH1 forms cis-clusters [Homo sapiens] [Reaction:9817325] CDH1 associates with CTNND1 [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-06-18
reviewed	[InstanceEdit:9975417] Raptis, Leda, 2025-11-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9934493] R-HSA-9934486.2
summation	[Summation:9934484] CTNNA1 (α-catenin) is responsible for the recruitment of F-a...
(hasEvent)	[Pathway:9764561] Regulation of CDH1 Function [Homo sapiens] [Pathway:9958825] Activation of STAT3 by cadherin engagement [Homo sapiens]
(precedingEvent)	[Reaction:9934294] CDH1-associated CTNNA1 binds VCL [Homo sapiens] [Reaction:9934410] CDH1 forms homotypic trans-dimers [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984630] Update Tracker - [Reaction:9934486] CDH1-associated CTNNA1 binds F-actin - v96:[modifyText]
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No pathways have been reviewed or authored by CDH1-associated CTNNA1 binds F-actin (9934486)