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Details on Person DDB1:CUL4:RBX1:DTL ubiquitinylates CRY1

Class:Id	BlackBoxEvent:9933118
_displayName	DDB1:CUL4:RBX1:DTL ubiquitinylates CRY1
_timestamp	2024-12-28 18:59:24
authored	[InstanceEdit:9933132] May, Bruce, 2024-12-24
catalystActivity	[CatalystActivity:9933109] ubiquitin protein ligase activity of DDB1:CUL4:RBX1:DTL:p-S-CRY1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9933134] May, Bruce, 2024-12-24
edited	[InstanceEdit:9933132] May, Bruce, 2024-12-24
inferredFrom	[BlackBoxEvent:9933119] Ddb1:Cul4a:Skp1:Rbx1 ubiquitinylates p-S-Cry1 [Mus musculus]
input	[Complex:9933115] DDB1:CUL4:RBX1:DTL:p-S-CRY1 [nucleoplasm] [Homo sapiens] [Complex:8937543] Ub:UBE2D1 [nucleoplasm] [Homo sapiens] [Complex:8937543] Ub:UBE2D1 [nucleoplasm] [Homo sapiens] [Complex:8937543] Ub:UBE2D1 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9933330] May, Bruce, 2024-12-28
name	DDB1:CUL4:RBX1:DTL ubiquitinylates CRY1
output	[Complex:5655461] RBX1:CUL4:DDB1:DTL [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:174197] UBE2D1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:174197] UBE2D1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:174197] UBE2D1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9933120] K48polyUb-K565,p-S-CRY1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9933128] DDB1:CUL4:RBX1:DTL binds phosphorylated (?) CRY1 [Homo sapiens] [BlackBoxEvent:9909565] p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9933145] R-HSA-9933118.1
summation	[Summation:9933302] The SCF E3 ligase complex DDB1:CUL4:RBX1:DTL polyubiquitinyl...
(hasEvent)	[Pathway:9934865] Circadian clock update - do not release [Homo sapiens]
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No pathways have been reviewed or authored by DDB1:CUL4:RBX1:DTL ubiquitinylates CRY1 (9933118)