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Details on Person CANX binds Glu1Man9GlcNAc2-CDH1

Class:IdBlackBoxEvent:9932988
_displayNameCANX binds Glu1Man9GlcNAc2-CDH1
_doReleaseTRUE
_timestamp2025-06-05 18:25:17
authored[InstanceEdit:9932987] Orlic-Milacic, Marija, 2024-12-21
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:9932987] Orlic-Milacic, Marija, 2024-12-21
edited[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17
input[EntityWithAccessionedSequence:9932989] CANX [endoplasmic reticulum membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9932915] Glu1Man9GlcNAc2-CDH1(23-882) [endoplasmic reticulum membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimericFALSE
literatureReference[LiteratureReference:9816239] Unglycosylation at Asn-633 made extracellular domain of E-cadherin folded incorrectly and arrested in endoplasmic reticulum, then sequentially degraded by ERAD
modified[InstanceEdit:9932996] Orlic-Milacic, Marija, 2024-12-21
[InstanceEdit:9935645] Orlic-Milacic, Marija, 2025-01-17
[InstanceEdit:9935647] Orlic-Milacic, Marija, 2025-01-17
[InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20
[InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
[InstanceEdit:9954118] Orlic-Milacic, Marija, 2025-06-05
nameCANX binds Glu1Man9GlcNAc2-CDH1
negativePrecedingEvent[NegativePrecedingEvent:9954090] Futile Cycle: Glucosidase II removes glucose residue from Glu1Man9GlucNAc2-CDH1
output[Complex:9932986] CANX:Glu1Man9GlcNAc2-CDH1 [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent
releaseDate2025-06-18
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9932992] R-HSA-9932988.2
summation[Summation:9932995] After Glucosidase II complex-mediated removal of the second ...
(hasEvent)[Pathway:9768727] Regulation of CDH1 posttranslational processing and trafficking to plasma membrane [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9932913] Glucosidase II removes glucose residue from Glu1Man9GlucNAc2-CDH1 [Homo sapiens]
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No pathways have been reviewed or authored by CANX binds Glu1Man9GlcNAc2-CDH1 (9932988)