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Details on Person EmrE dimer exports xenobiotics to periplasm

Class:Id	Reaction:9931565
_displayName	EmrE dimer exports xenobiotics to periplasm
_doRelease	TRUE
_timestamp	2025-05-21 07:40:03
authored	[InstanceEdit:9931201] Stephan, Ralf, 2024-12-11
catalystActivity	[CatalystActivity:9931578] xenobiotic transmembrane transporter activity of EmrE dimer [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9931555] Stephan, Ralf, 2024-12-12
disease	[Disease:3134792] bacterial infectious disease
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input	[DefinedSet:9931557] EmrE cargo [cytosol] [SimpleEntity:8858135] H+ [periplasmic space] [SimpleEntity:8858135] H+ [periplasmic space]
internalReviewed	[InstanceEdit:9937184] Matthews, Lisa, 2025-01-30
isChimeric	FALSE
literatureReference	[LiteratureReference:9931165] Disinfectant resistance in bacteria: Mechanisms, spread, and resolution strategies [LiteratureReference:9931566] Cloning of the ethidium efflux gene from Escherichia coli [LiteratureReference:9931564] Cloning and characterization of the mvrC gene of Escherichia coli K-12 which confers resistance against methyl viologen toxicity [LiteratureReference:9931573] Analyzing conformational changes in the transport cycle of EmrE
modified	[InstanceEdit:9933047] Stephan, Ralf, 2024-12-23 [InstanceEdit:9937183] Stephan, Ralf, 2025-01-30 [InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	EmrE dimer exports xenobiotics to periplasm
output	[DefinedSet:9931568] EmrE cargo [periplasmic space] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9931597] R-HSA-9931565.1
summation	[Summation:9931577] E.coli EmrE dimer transports molecules of polyaromatic catio...
(hasEvent)	[Pathway:9913143] Antimicrobial resistance [Homo sapiens]
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No pathways have been reviewed or authored by EmrE dimer exports xenobiotics to periplasm (9931565)