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Details on Person May, Bruce, 2024-12-12

Class:IdInstanceEdit:9931548
_displayNameMay, Bruce, 2024-12-12
_timestamp2024-12-12 08:07:34
author[Person:203835] May, Bruce
dateTime2024-12-12 08:07:09
(modified)[RegulationReference:9642203] Positive gene expression regulation by 'RORA:Coactivator:ARNTL gene [nucleoplasm]' Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors
[RegulationReference:9642686] Negative regulation by 'Nr1d1:heme:Corepressors:Arntl gene [nucleoplasm]' The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene
[PositiveGeneExpressionRegulation:9909366] Positive gene expression regulation by 'p-S90-BMAL1:p-T451,T461-CLOCK:CREBBP:KMT2A:PER3 gene [nucleoplasm]'
[Pathway:9909396] Circadian clock [Homo sapiens]
[Reaction:9911560] RORA,B,C, EP300, PPARGC1A, NRIP1 bind BMAL1 (ARNTL) gene [Homo sapiens]
[Summation:9911566] RORA, RORB, or RORC bind ROR responsive elements (RREs, RORE...
[Summation:9911568] Rora, Rorb, or Rorc bind ROR responsive elements (RREs, RORE...
[BlackBoxEvent:9911570] Rora,b,c positivley regulates and Nr1d1 (Rev-erba) negatively regulates expression of Bmal1 (Arntl) [Mus musculus]
[PositiveGeneExpressionRegulation:9911571] Positive gene expression regulation by 'RORA,B,C:Coactivator:BMAL1 gene [nucleoplasm]'
[Reaction:9911575] Rora,b,c, Ep300, Ppargc1a bind Bmal1 (Arntl) gene [Mus musculus]
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(structureModified)[Pathway:9909396] Circadian clock [Homo sapiens]
[BlackBoxEvent:9911570] Rora,b,c positivley regulates and Nr1d1 (Rev-erba) negatively regulates expression of Bmal1 (Arntl) [Mus musculus]
[BlackBoxEvent:9923018] Phosphorylated BMAL1:CLOCK positively regulates expression of NR1D1 (REV-ERBA) [Homo sapiens]
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No pathways have been reviewed or authored by May, Bruce, 2024-12-12 (9931548)