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Details on Person CK2 phosphorylates CD274

Class:IdReaction:9931418
_displayNameCK2 phosphorylates CD274
_doReleaseTRUE
_timestamp2025-08-26 07:56:58
authored[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26
[InstanceEdit:9927346] Tiwari, Krishna, 2024-11-05
catalystActivity[CatalystActivity:9931410] protein serine/threonine kinase activity of CK2 [cytosol]
compartment[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created[InstanceEdit:9931398] Tiwari, Krishna, 2024-12-11
edited[InstanceEdit:9962761] Gillespie, Marc E, 2025-08-08
input[EntityWithAccessionedSequence:9930703] CD274 [endoplasmic reticulum membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9931412] Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function
modified[InstanceEdit:9936028] Tiwari, Krishna, 2025-01-20
[InstanceEdit:9936161] Tiwari, Krishna, 2025-01-21
[InstanceEdit:9937955] Tiwari, Krishna, 2025-02-10
[InstanceEdit:9963582] Gillespie, Marc E, 2025-08-14
[InstanceEdit:9964107] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964125] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964126] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9965199] Matthews, Lisa, 2025-08-26
nameCK2 phosphorylates CD274
output[EntityWithAccessionedSequence:9931388] p-T285,T290-CD274 [endoplasmic reticulum membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2025-09-18
reviewed[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9931427] R-HSA-9931418.1
structureModified[InstanceEdit:9936028] Tiwari, Krishna, 2025-01-20
[InstanceEdit:9936161] Tiwari, Krishna, 2025-01-21
summation[Summation:9937952] Casein Kinase 2 (CK2) phosphorylates and stabilizes PD-L1 (C...
(hasEvent)[Pathway:9929491] SPOP-mediated proteasomal degradation of PD-L1(CD274) [Homo sapiens]
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