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Details on Person UniProt:P13036 fecA
| Class:Id | ReferenceGeneProduct:9931035 |
|---|---|
| _chainChangeLog | signal peptide:1-33 for 9931035 added on Fri Feb 21 2025;chain:34-774 for 9931035 added on Fri Feb 21 2025 |
| _displayName | UniProt:P13036 fecA |
| _timestamp | 2025-02-21 19:17:41 |
| chain | signal peptide:1-33 chain:34-774 |
| checksum | 16B5B510276C3B09 |
| comment | FUNCTION FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.SUBUNIT Interacts (via periplasmic N-terminus) with FecR (via periplasmic C-terminus).INTERACTION For induction, the TonB and the ExbB proteins have to be active. Regulation by the iron level mediated by the Fur protein and induction by citrate plus iron suggest that the Fe(3+) dicitrate complex must enter the periplasm where it binds to a transmembrane protein, which regulates transcription of the fec genes directly or via a further inductor. Induced 2-fold by hydroxyurea (PubMed:20005847).SIMILARITY Belongs to the TonB-dependent receptor family. |
| created | [InstanceEdit:9931029] Stephan, Ralf, 2024-12-09 |
| description | recommendedName: Fe(3+) dicitrate transport protein FecA alternativeName: Iron(III) dicitrate transport protein FecA |
| geneName | fecA b4291 JW4251 |
| identifier | P13036 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell outer membrane Direct protein sequencing Ion transport Iron Iron transport Membrane Receptor Reference proteome Signal TonB box Transmembrane Transmembrane beta strand Transport |
| modified | [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | fecA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | FECA_ECOLI Q2M624 |
| sequenceLength | 774 |
| species | [Species:159879] Escherichia coli |
| (referenceEntity) | [EntityWithAccessionedSequence:9931033] FecA [cell outer membrane] [Escherichia coli] |
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No pathways have been reviewed or authored by UniProt:P13036 fecA (9931035)
